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東京大学大学院 医学系研究科 公共健康医学専攻 臨床疫学・経済学分野の変更点

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!!!ようこそ、臨床疫学・経済学分野へ
臨床疫学・経済学分野は[東京大学大学院医学系研究科公共健康医学専攻(School of Public Health, SPH)|http://www.m.u-tokyo.ac.jp/sph/]の一分野として2007年4月に開設されました。

臨床疫学は、臨床の問題を扱うという点で極めて臨床的であると同時に、疫学の手法を用いるという点で極めて公衆衛生的です。医学の国際的潮流であるEBM(Evidence-based medicine, 根拠に基づく医療)を実践する基盤となる学問領域として、その重要性は増大する一方です。

また、超高齢社会のもとでの医療資源の制約と医療の効率化の社会的要請を背景として、医療経済学の重要性はかつてないほど広く認識されるに至っています。

臨床は個々の患者の生命を救い健康を回復維持することが主眼です。一方、経済学では社会全体での最適な資源配分のあるべき姿を議論します。両者はそのアプローチの方法こそ違いますが、人々の幸福を実現することを目指すという根本的な目的部分では通底します。

本学の公共健康医学専攻(SPH)における教育の目的は、専門性と公共性を兼ね備えた公衆衛生のプロを養成することです。中でも臨床疫学・経済学を実践する専門家の育成は国家的急務であるといえるでしょう。

本分野は、疫学と経済学という背景の異なる2つの数量的分析手法と関連の社会科学的理論を裏付けとし、境界領域的な応用学問分野として、実証データに基づいた研究と実践・教育を志向しています。


!!!スタッフ
,ポスト, スタッフ, 研究専攻 
,教授,康永秀生,臨床疫学 医療経済・政策学 公衆衛生学
,助教,松居宏樹,臨床疫学 医療経済・政策学 リハビリテーション医学

!!!学生・研究員
,学年, 氏名,専門領域,研究テーマ,メッセージ
,博士課程1年,道端伸明,,,
,博士課程1年,山名隼人,,,
,修士課程2年,小田切啓之,消化器内科学,消化管疾患の疫学、内視鏡診断・治療,
,修士課程2年,笹渕裕介,,,
,修士課程2年,鈴木さやか,耳鼻咽喉科学,耳鼻科疾患の疫学,
,修士課程2年,田上隆,救急・集中治療、一般外科・外傷外科,心肺蘇生法、循環呼吸動態、災害医療,
,修士課程1年,石丸美穂,,,
,修士課程1年,大野幸子,,,
,修士課程1年,佐上徹,,,
,修士課程1年,平嶋純子,,,
,修士課程1年,森田光治良,,,
,客員研究員,磯貝俊明,,,
,客員研究員,長沼通郎,,,,

!!!連絡先
*東京大学大学院医学系研究科   公共健康医学専攻 臨床疫学・経済学分野
**113-0033 東京都文京区本郷7-3-1 東京大学医学部2号館本館 3階
**Phone:03-5841-1887
**Fax:03-5841-1888
**内線:21887 (※東京大学内の皆様用)
**E-mail: yasunagah-tky@umin.ac.jp



!!!本講座の活動内容
!日本版診断群分類(Diagnosis Procedure Combination, DPC)に基づくナショナル・データベースの整備とその活用
本講座スタッフは厚生労働科学研究のDPC 研究班のメンバーとして、DPCデータのマネージメントとその高度利用を担っております。具体的には、DPC研究班が集める毎年約700万件の退院症例データを蓄積するデータベースを構築し、管理・運営するシステムを確立しています。
さらに国内の各領域の研究者と連携し、DPCデータを用いた臨床疫学研究、ヘルス・サービス・リサーチ、医療経済・政策研究を推進しております。

!その他の研究活動
+医師供給の地域間・診療科間格差とその要因に関する研究
+保健医療サービスの経済評価に関する研究



!教育
東京大学大学院医学系研究科公共健康医学専攻(SPH)では、臨床疫学講義、保健医療経済学講義、医療技術評価学演習および臨床疫学・経済学演習を担当しています。

臨床疫学研究のテーマは、日常臨床の中に潜んでいます。Clinical practiceからresearch questionを紡ぎ出し、研究仮説を立て、適切なデザインを構築し、利用可能なデータから意味のある分析結果を出し、臨床的に妥当な解釈を行います。臨床疫学講義では、これら一連のプロセスを遂行するために不可欠となる臨床疫学の理論および実践的な方法論を身につけます。

保健医療経済学講義では、医療経済学の基礎を身につけた上で、医療経済学の考え方や理論について理解を深めてもらいます。医療技術評価学演習では、医療技術の有効性評価および費用効果分析について実践的な知識と技術を身につけます。

臨床疫学・経済学演習では、学生各人が具体的な臨床的関心あるいは公衆衛生学的関心に基づき、研究のproposal writingができる実践的なスキルを身につけます。さらに医学英語論文の書き方の基本を学びます。


!!!論文 
[2014]
+Chikuda H Yasunaga H, Takeshita K, Horiguchi H, Kawaguchi H, Ohe K, Fushimi K, Tanaka S. Mortality and morbidity after high-dose methylprednisolone treatment in patients with acute cervical spinal cord injury: A propensity matched analysis using a nationwide administrative database. Emergency Medicine Journal 2014;31(3):201-6
+Chikuda H Yasunaga H, Takeshita K, Horiguchi H, Kawaguchi H, Fushimi K, Tanaka S. Ischemic Stroke after Cervical Spine Injury: Analysis of 11,005 Patients Using the Japanese Diagnosis Procedure Combination Database. Spine Journal 2014 14(10):2275-80. 
+Hamada T, Yasunaga H, Nakai Y, Isayama H, Horiguchi H, Fushimi K, Koike K. Impact of hospital volume on outcomes in acute pancreatitis: a study using a nationwide administrative database. J Gastroenterol 2014;49:148-55.
+Hamada T, Nakai Y, Yasunaga H, Isayama H, Matsui H, Takahara N, Sasaki T, Takagi K, Watanabe T, Yagioka H, Kogure H, Arizumi T, Yamamoto N, Ito Y, Hirano K, Tsujino T, Tada M, Koike K. Prognostic nomogram for nonresectable pancreatic cancer treated with gemcitabine-based chemotherapy. British Journal of Cancer 2014;110(8):1943-9.
+Hamada T, Yasunaga H, Nakai Y, Isayama H, Horiguchi H, Matsuda S, Fushimi K, Koike K. Severe bleeding and perforation are rare complications of endoscopic ultrasound-guided fine needle aspiration for pancreatic masses: An analysis of 3,090 patients from 212 hospitals. Gut and Liver 2014;8(2):215-8.
+Hamada T, Yasunaga H, Nakai Y, Isayama H, Horiguchi H, Fushimi K, Koike K. Impact of Antithrombotic Agents on Severe Bleeding after Percutaneous Transhepatic Drainage of the Biliary System: Analysis of 34,606 Cases from a Japanese Nationwide Administrative Database. Radiology 2014 epub
+Hasegawa W, Yamauchi Y, Yasunaga H, Sunohara M, Jo T, Matsui H, Fushimi K, Takami K, Nagase T. Clinical Features of 280 Hospitalized Patients with Lymphangioleiomyomatosis in Japan. Respirology 2014 in press
+Hasegawa W, Yamauchi Y, Yasunaga H, Sunohara M, Jo  T, Matsui H, Fushimi K, Takami K, Nagase T. Factors affecting mortality following emergency admission for chronic obstructive pulmonary disease. BMC Pulmonary Medicine 2014 in press
+Inokuchi H, Yasunaga H, Nakahara Y, Horiguchi H, Ogata N, Fujitani J, Matsuda S, Fushimi K, Haga N. Effect of Rehabilitation on Mortality of Patients with Guillain-Barre Syndrome: A Propensity-matched Analysis Using a Nationwide Database. Eur J Phys Rehabil Med 2014;50(4):439-46
+Isogai T, Yasunaga H, Matsui H, Tanaka H, Ueda T, Horiguchi H, Fushimi K. Out-of-hospital versus in-hospital Takotsubo cardiomyopathy: analysis of 3719 patients in the Diagnosis Procedure Combination database in Japan. International Journal of Cardiology 2014;176(2):413-7.
+Isogai T, Yasunaga H, Matsui H, Tanaka H, Horiguchi H, Fushimi K. Effectiveness  of inferior vena cava filters on in-hospital mortality as an adjuvant to antithrombotic therapy for pulmonary embolism: propensity score and instrumental variable analyses. Am J Med 2014 in press
+Isogai T, Yasunaga H, Matsui H, Ueda T, Tanaka H, Horiguchi H, Fushimi K. Hospital Volume and Cardiac Complications of Endomyocardial Biopsy: A Retrospective Cohort Study of 9508 Adult Patients Using a Nationwide Inpatient Database in Japan. Clinical Cardiology 2014 in press
+Isogai T, Yasunaga H, Matsui H, Tanaka H, Ueda T, Horiguchi H, Fushimi K. Effect of weekend admission for acute myocardial infarction on in-hospital mortality: a retrospective cohort study. International Journal of Cardiology 2014 in press
+Isogai T, Yasunaga H, Matsui H, Tanaka H, Ueda T, Horiguchi H, Fushimi K. Serious Cardiac Complications in Coronary Spasm Provocation Tests Using Acetylcholine or Ergonovine: Analysis of 21,512 Patients from the Diagnosis Procedure Combination Database in Japan. Clinical Cardiology 2014 in press
+Iwagami M, Yasunaga H, Doi K, Horiguchi H, Fushimi K, Matsubara T, Yahagi N, Noiri E. Postoperative Polymyxin B Hemoperfusion and Mortality in Patients with Abdominal Septic Shock: A Propensity-Matched Analysis. Crit Care Med 2014;42(5):1187-93 
+Iwagami M, Yasunaga H, Noiri E, Horiguchi H, Fushimi K, Matsubara T, Yahagi N, Nangaku M. Choice of renal replacement therapy modality in intensive care units: data from a Japanese Nationwide Administrative Claim Database. Journal of Critical Care 2014 in press
+Kumamaru H, Tsugawa Y, Horiguchi H, Kumamaru KK, Hashimoto H, Yasunaga H. Association between Hospital Case Volume and Mortality in Non-elderly Pneumonia Patients Stratified by Severity: a Retrospective Cohort Study. BMC Health Services Research 2014 ;14:302 
+Lee SL, Hashimoto H, Kohro T, Horiguchi H, Koide D, Komuro I, Fushimi K, Yamazaki T, Yasunaga H. Influence of Municipality-Level Mean Income on Access to Aortic Valve Surgery: A Cross-Sectional Observational Study under Japan’s Universal Health-Care Coverage. Plos One 2014 ;9(10):e111071
+Matsumoto M, Koike S, Matsubara S, Kashima S, Ide H, Yasunaga H. Selection and concentration of obstetric facilities in Japan: a longitudinal study based on the national census data. Journal of Obstetrics and Gynaecology Research 2014 in presss
+Michihata N, Matsui H, Fushimi K, Yasunaga H. Comparison between Enteral Nutrition and Intravenous Hyperalimentation in Patients with Eating Disorders: Results from the Japanese Diagnosis Procedure Combination Database. Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity 2014 ;19(4):473-8
+Momosaki R, Yasunaga H, Matsui H, Abo M. Effect of Dysphagia Rehabilitation on Oral Intake in Elderly Patients with Aspiration Pneumonia. Geriatrics & Gerontology International 2014 epub
+Momosaki R, Yasunaga H, Matsui H, Horiguchi H, Fushimi K, Abo M. Effect of Early Rehabilitation by Physical Therapists on In-hospital Mortality after Aspiration Pneumonia in the Elderly. Archives of Physical Medicine and Rehabilitation 2014 epub
+Naganuma M, Matsui H, Fushimi K, Yasunaga H. Clinical Features of Isolated Dissections of Abdominal Aortic Branches. Heart and Vessels 2014 in press
+Niikura R, Yasunaga H, Yamaji Y, Horiguchi H, Fushimi K, Yamada A, Hirata Y, Koike K. Factors affecting in-hospital mortality in patients with lower gastrointestinal bleeding: a retrospective study using a national database in Japan. J Gasrtoenterol 2014 epub
+Odagiri H, Matsui H, Fushimi K, Kaise M, Yasunaga H. Factors predicting perforation related to diagnostic balloonassisted enteroscopy: analysis of the Diagnosis Procedure Combination database in Japan. Endoscopy 2014 in press
+Ogura K, Yasunaga H, Horiguchi H, Fushimi K, Tanaka S, Kawano H. Nomogram Predicting Severe Adverse Events after Musculoskeletal Tumor Surgery: Analysis of a National Administrative Database. Annals of Surgical Oncology 2014;21(11):3564-71
+Ogura K, Yasunaga H, Horiguchi H, Fushimi K, Kawano H. What Is the Effect of Advanced Age and Comorbidity on Postoperative Morbidity and Mortality After Musculoskeletal Tumor Surgery? Clinical Orthopaedics and Related Research 2014 ;472(12):3971-8 
+Sako A, Yasunaga H, Horiguchi H, Fushimi K, Yanai H, Uemura N. Prevalence and In-hospital Mortality of Gastrostomy and Jejunostomy in Japan: A Retrospective Study Using a National Administrative Database. Gastrointestinal Endoscopy 2014;80:88-96.
+Sasabuchi Y, Yasunaga H, Sanui M, Alan LT. The dose-response relationship between body mass index and mortality in patients admitted to the intensive care unit with and without mechanical ventilation. Respiratory Care 2014 in press
+Sato M, Tateishi R, Yasunaga H, Horiguchi H, Yoshida H, Matsuda S, Fushimi K, Koike K. Acute liver disease in Japan – a nationwide analysis of the Japanese Diagnosis Procedure Combination database. J Gastroenterol 2014;49(3):547-54
+Sato M, Tateishi R, Yasunaga H, Horiguchi H, Yoshida H, Matsuda S, Fushimi K, Koike K. Variceal hemorrhage – Analysis of 9987 cases from a Japanese nationwide database. Hepatology Research 2014 epub
+Sugihara T, Yasunaga H, Horiguchi H, Fujimura T, Fushimi K, Yu C, Kattan M, Homma Y. Factors Affecting the Choice of Ureterostomy, Ileal Conduit and Continent Reservoir after Radical Cystectomy: Japanese Series. Int J Clin Oncol 2014 epub
+Sugihara T, Yasunaga H, Horiguchi H, Matsuda S, Fushimi K, Kattan M, Homma Y. Does mechanical bowel preparation ameliorate damage from rectal injury in radical prostatectomy? Analysis of 151 rectal injury cases. Int J Urol 2014;21(6):566-70
+Sugihara T, Yasunaga H, Horiguchi H, Fushimi K, Dalton J, Schold J, Kattan M, Homma Y. Performance comparisons in major uro-oncological surgeries between the United States and Japan. Int J Urol 2014 ;21(11):1145-50
+Sugihara T, Yasunaga H, Horiguchi H, Matsui H, Nishimatsu H, Nakagawa T, Fushimi K, Kattan MW, Homma Y. Comparison of Perioperative Outcomes Including Severe Bladder Injury Between Monopolar and Bipolar Transurethral Resection of Bladder Tumors: A Population-Based Comparison. Journal of Urology 2014;192(5):1355-9.
+Sugihara T, Yasunaga H, Horiguchi H, Matsui H, Fujimura T, Nishimatsu H, Fukuhara H, Kume H, Changhong Y, Kattan MW, Fushimi K, Homma Y. Robot-assisted versus other types of radical prostatectomy: population-based safety and cost comparison in Japan, 2012–2013. Cancer Science 2014 epub
+Sugihara T, Yu C, Kattan MW, Yasunaga H, Ihara H, Onozawa M, Hinotsu S, Akaza H. Long-Term Survival in Extremely Advanced Prostate Cancer Patients Diagnosed with Prostate Specific Antigen over 500 ng/mL. Japanese Journal of Clinical Oncology 2014 epub
+Sumitani M, Yasunaga H, Uchida K, Horiguchi H, Nakamura M, Ohe K, Fushimi K, Matsuda S, Yamada Y. Perioperative factors affecting the occurrence of acute complex regional pain syndrome following limb bone fracture surgery: Data from the Japanese Diagnosis Procedure Combination database. Rheumatology 2014;53(7):1186-93
+Suzuki S, Yasunaga H, Matsui H, Horiguchi H, Fushimi K, Yamasoba T. Impact of Systemic Steroids on Post-Tonsillectomy Bleeding: Analysis of 61430 Patients using a National Inpatient Database in Japan. JAMA Otolaryngology-Head & Neck Surgery 2014 ;140(10):906-10.
+Tagami T, Matsui H, Horiguchi H, Fushimi K, Yasunaga H. Antithrombin and mortality in severe pneumonia patients with sepsis-associated disseminated intravascular coagulation: an observational nationwide study. J Thrombosis Haemost 2014 ;12(9):1470-9
+Tagami T, Matsui H, Horiguchi H, Fushimi K, Yasunaga H. Low-dose corticosteroid use and mortality in severe community-acquired pneumonia patients Eur Respir J. 2014 epub
+Tagami T, Matsui H, Horiguchi H, Fushimi K, Yasunaga H. Thoracic aortic injury in Japan: a nationwide retrospective cohort study. Circ J 2014 in press
+Tagami T, Matsui H, Horiguchi H, Fushimi K, Yasunaga H. Recombinant human soluble thrombomodulin and mortality in severe pneumonia patients with sepsis-associated disseminated intravascular coagulation: an observational nationwide study. J Thrombosis Haemost 2014 in press
+Taguchi M, Kubo T, Yamamoto M, Muramatsu K, Yasunaga H, Horiguchi H, Fujimori K, Matsuda S, Fushimi K, Harada M. Body Mass Index Influences the Outcome of Acute Pancreatitis: An Analysis Based on the Japanese Administrative Database. Pancreas 2014 ;43(6):863-6. 
+Takagi T, Sugihara T, Yasunaga H, Horiguchi H, Fushimi K, Kattan MW, Homma Y, Tanabe K. Perioperative Outcomes after Cytoreductive Nephrectomy for Metastatic Renal Cell Carcinoma, According to Clinical Stage: A Population-Based Analysis. Int J Urol 2014 ;21(8):770-5. 
+Takeuchi M, Tomomasa T, Yasunaga H, Horiguchi H, Fushimi K. Descriptive Epidemiology of Children Hospitalized for Inflammatory Bowel Disease in Japan. Pediatrics International 2014 in press.
+Tsuda Y, Yasunaga H, Horiguchi H, Fushimi K, Kawano H, Tanaka S. Effects of Fondaparinux on Pulmonary Embolism following Hemiarthroplasty for Femoral Neck Fracture: a Retrospective Observational Study Using the Japanese Diagnosis Procedure Combination Database. J Orthop Sci 2014 epub
+Uchida K, Yasunaga H, Sumitani M, Horiguchi H, Fushimi K, Yamada Y. Effects of Remifentanil on In-hospital Mortality and Length of Stay Following Clipping of Intracranial Aneurysm: A Propensity Score Matched Analysis. J Neurosurg Anesth 2014 ;26(4):291-8. 
+Uehara K, Yasunaga H, Morizaki Y, Horiguchi H, Fushimi K, Tanaka S. Necrotising soft-tissue infections of the upper limb: risk factors for amputation and death. Bone Joint J 2014;96-B(11):1530-4.  
+Uematsu H, Hashimoto H, Iwamoto T, Horiguchi H, Yasunaga H. Impact of guideline-concordant microbiological testing on outcomes of pneumonia. Int J Quality Health Care 2014;26(1):100-7.
+Wada T, Yasunaga H, Inokuchi R, Horiguchi H, Fushimi K, Matsubara T, Nakajima S, Yahagi N. Relationship between hospital volume and early outcomes in acute ischemic stroke patients treated with recombinant tissue plasminogen activator. International Journal of Stroke 2014 epub
+Wada T, Yasunaga H, Inokuchi R, Horiguchi H, Fushimi K, Matsubara T, Nakajima S, Yahagi N. Effects of Edaravone on Early Outcomes in Acute Ischemic Stroke Patients Treated with Recombinant Tissue Plasminogen Activator. Journal of the Neurological Sciences 2014 ;345(1-2):106-11. 
+Yamamoto H, Hashimoto H, Nakamura Horiguchi H, Yasunaga H. Relationship between hospital volume and hemorrhagic complication after percutaneous renal biopsy: results from the Japanese Diagnosis Procedure Combination Database. Clinical and Experimental Nephrology 2014 epub
+Yamana H, Matsui H, Fushimi K, Yasunaga H. Treatment options and outcomes of hospitalised tuberculosis patients: a nationwide study. The International Journal of Tuberculosis and Lung Disease 2014 in press
+Yamauchi Y, Hasegawa W, Hideo Yasunaga H, Sunohara M, Taisuke Jo T, Takami K, Matsui H, Fushimi K, Nagase T. Paradoxical association between body mass index and in-hospital mortality in elderly patients with chronic obstructive pulmonary disease in Japan. International Journal of Chronic Obstructive Pulmonary Disease 2014 in press
+Yasunaga H, Matsui H, Horiguchi H, Fushimi K, Matsuda S. Clinical Epidemiology and Health Services Research using the Diagnosis Procedure Combination Database in Japan. Asian Pacific Journal of Disease Management 2014 in press
+Yoshioka R, Yasunaga H, Hasegawa K, Horiguchi H, Fushimi K, Aoki T, Sakamoto Y, Sugawara Y, Kokudo N. Hospital volume affects in-hospital mortality, length of stay, and total costs after pancreaticoduodenectomy: Analysis of data from 10,652 patients from the Japanese Diagnosis Procedure Combination database. Brit J Surg 2014;101(5):523-9. 


[2013]
+Yasunaga H, Horiguchi H, Kuwabara K, Matsuda S, Fushimi K, Hashimoto H, Ayanian JZ. Outcomes After Laparoscopic or Open Distal Gastrectomy for Early-stage Gastric Cancer: A Propensity-matched Analysis. Ann Surg 2013;257(4):640-6
+Yasunaga H, Horiguchi H, Matsuda S, Fushimi K, Hashimoto H, Ayanian JZ. Body mass index and outcomes following gastrointestinal cancer surgery in Japan: A retrospective cohort study. Brit J Surg 2013;100:1335–43
+Yasunaga H, Horiguchi H, Hashimoto H, Matsuda S, Fushimi K. Effect and Cost of Treatment for Acute Pancreatitis With or Without Gabexate Mesylate: A Propensity Score Analysis Using a Nationwide Administrative Database. Pancreas 2013;42(2):260-4
+Akahane M, Tanabe S, Ogawa T, Koike S, Horiguchi H, Yasunaga H, Imamura T. Characteristics and Outcomes of Pediatric Out-of-Hospital Cardiac Arrest by Scholastic Age Category. Pediatric Critical Care Medicine 2013;14(2):130-6 
+Akiyama T, Chikuda H, Yasunaga H, Horiguchi H, Fushimi K, Saita K. Incidence and Risk Factors for Mortality of Vertebral Osteomyelitis: A Retrospective Analysis Using the Japanese Diagnosis Procedure Combination Database. BMJ Open 2013;3:e002412.
+Chikuda H, Yasunaga H, Horiguchi H, Takeshita K, Sugita S, Taketomi S, Fushimi K, Tanaka S. Impact of Age and Comorbidity Burden on Mortality and Major Complications in Older Adults Undergoing Orthopaedic Surgery: An Analysis Using the Japanese Diagnosis Procedure Combination Database. BMC Musculoskeletal Disorders 2013;14(1):173
+Fukuda T, Yasunaga H, Horiguchi H, Ohe K, Fushimi K, Matsubara T, Yahagi N. Health care costs related to out-of-hospital cardiopulmonary arrest in Japan. Resuscitation 2013 ;84(7):964-9.
+Hamada T, Yasunaga H, Nakai Y, Isayama H, Horiguchi H, Matsuda S, Fushimi K, Koike K. Rarity of severe bleeding and perforation in endoscopic ultrasound-guided fine needle aspiration for submucosal tumors. Digestive Diseases Science 2013;58:2634-8.
+Hamada T, Yasunaga H, Nakai Y, Isayama H, Horiguchi H, Matsuda S, Fushimi K, Koike K. Continuous regional arterial infusion for acute pancreatitis: A propensity score analysis using a nationwide administrative database. Critical Care 2013;17(5):R214.
+Hamada T, Yasunaga H, Nakai Y, Isayama H, Horiguchi H, Fushimi K, Ohe K, Koike K. Japanese Severity Score for Acute Pancreatitis Well Predicts In-hospital Mortality: A Nationwide Survey of 17,901 Cases. Journal of Gastroenterology 2013;48(12):1384–91
+Nakamura M, Yasunaga H, Ando S, Haraguchi T, Sugihara T, Horiguchi H, Ohe K, Matsuda S, Fushimi K. Length of mechanical restraint following haloperidol injections versus oral atypical antipsychotics for the initial treatment of acute schizophrenia: A Propensity-Matched Analysis from the Japanese Diagnosis Procedure Combination Database. Psychiatry Research 2013;209:412-6 
+Nakamura M, Yasunaga H, Shimada T, Horiguchi H, Matsuda S, Fushimi K. Body mass index and in-hospital mortality in anorexia nervosa: data from the Japanese Diagnosis Procedure Combination Database. Eating and Weight Disorders 2013;18(4):437-9. 
+Ogura K, Yasunaga H, Horiguchi H, Ohe K, Shinoda Y, Tanaka S, Kawano H. Incidence and risk factors for postoperative pulmonary embolism following primary musculoskeletal tumor surgery: Analysis of a national administrative database. Clin Orthop Relat Res 2013;471:3310-6.
+Ogura K, Yasunaga H, Horiguchi H, Ohe K, Shinoda Y, Tanaka S, Kawano H.  Impact of Hospital Volume on Postoperative Complications and In-hospital Mortality after Musculoskeletal Tumor Surgery: Analysis of a National Administrative Database. J Bone Joint Surg Am 2013;95(18):1684-91.
+Sone M, Mizunuma K, Nakajima Y, Yasunaga H, Ohtomo K. Job satisfaction, income, workload, workplace, and demographics of Japanese radiologists in the 2008 survey. Japanese Journal of Radiology 2013;31:364-70.
+Sugihara T, Yasunaga H, Horiguchi H, Nishimatsu H, Kume H, Ohe K, Matsuda S, Fushimi K, Homma Y. A Nomogram Predicting Severe Adverse Events after Ureteroscopic Lithotripsy: 12,372 Patients in Japanese National Series. BJU Int 2013;111(3):459-66
+Sugihara T, Yasunaga H, Horiguchi H, Fujimura T, Nishimatsu H, Kume H, Ohe K, Matsuda S, Fushimi K, Homma Y. Is mechanical bowel preparation in laparoscopic radical prostatectomy beneficial? An analysis of a Japanese national database. BJU Int 2013 ;112(2):E76-81.
+Sugihara T, Yasunaga H, Horiguchi H, Fujimura T, Nishimatsu H, Tsuru N, Kazuo S, Ohe K, Fushimi K, Homma Y. Regional, institutional and individual factors affecting selection of minimally invasive nephroureterectomy in Japan: A national database analysis. Int J Urol 2013 ;81(1):74-9
+Sugihara T, Yasunaga H, Horiguchi H, Tsuru N, Ihara H, Fujimura T, Nishimatsu H, Ohe K, Fushimi K, Homma Y. Comparisons of perioperative outcomes and costs between open and laparoscopic radical prostatectomy: a propensity-score matching analysis based on the Japanese Diagnosis Procedure Combination database. Int J Urol 2013;20:349-53.
+Sugihara T, Yasunaga H, Horiguchi H, Fujimura T, Nishimatsu H, Ohe K, Matsuda S, Fushimi K, Kattan MW, Homma Y. Does Mechanical Bowel Preparation Improve Quality of Laparoscopic Nephrectomy? Propensity Score-matched Analysis in Japanese Series. Urology 2013;81(1):74-9.
+Sugihara T, Yasunaga H, Horiguchi H, Tsuru N, Fujimura T, Nishimatsu H, Kume H, Ohe K, Matsuda S, Fushimi K, Homma Y. Wide Range and Variations in Minimally Invasive Surgery For Renal Malignancy in Japan: A Population Based Analysis. Int J Clin Oncol 2013;18:1070–1077.
+Sugihara T, Yasunaga H, Horiguchi H, Fujimura T, Nishimatsu H, Kume H, Ohe K, Matsuda S, Fushimi K, Homma Y. Longer operative time is associated with higher risk of severe complications after percutaneous nephrolithotomy: analysis of 1511 cases from a Japanese nationwide database. Int J Urol 2013;20(12):1193-8.
+Takeuchi M, Yasunaga H, Horiguchi H, Hashimoto H, Matsuda S. Pyloromyotomy versus intravenous atropine therapy for the treatment of infantile pyloric stenosis: an analysis using nationwide hospital discharge database. Pediatrics International 2013;55(4):488-91
+Takeuchi M, Yasunaga H, Horiguchi H, Matsuda S. The Burden of Epiglottitis Among Japanese Children Before the Vaccination Era: an Analysis Using a Nationwide Administrative Database. Journal of Infection and Chemotherapy 2013;19:876-9.
+Tanabe S, Ogawa T, Akahane M, Koike S, Horiguchi H, Yasunaga H, Mizoguchi T, Hatanaka T, Yokota H, Imamura T. Comparison of Neurological Outcome between Tracheal Intubation and Supraglottic Airway Device Insertion of Out-of-hospital Cardiac Arrest Patients: A Nationwide, Population-based, Observational Study. Journal of Emergency Medicine 2013;44(2)389-397. 
+Tsugawa Y, Kumamaru H, Yasunaga H, Hashimoto H, Horiguchi H, Ayanian JZ. The Association of Hospital Volume with Mortality and Costs of Care for Acute Stroke in Japan. Medical Care 2013;51:782–8.


[2012]
+Yasunaga H, Horiguchi H, Matsuda S, Fushimi K, Hashimoto H, Ohe K, Kokudo N.  Relationship between hospital volume and operative mortality for liver resection: data from the Japanese Diagnosis Procedure Combination database.  Hepatol Res 2012;42(11):1073-1080
+Yasunaga H, Hashimoto H, Horiguchi H, Miyata S, Matsuda S. Variation in cancer surgical outcomes associated with physician and nurse staffing: a retrospective observational study using the Japanese Diagnosis Procedure Combination Database. BMC Health Serv Res 2012;12:129.
+Yasunaga H, Horiguchi H, Hashimoto H, Matsuda S, Fushimi K. The Burden of Clostridium difficile–Associated Disease following Digestive Tract Surgery in Japan. J Hosp Infect  2012 ;82(3):175-80.
+Akahane M, Ogawa T, Tanabe S, Koike S, Horiguchi H, Yasunaga H, Imamura T.  Impact of Telephone Dispatcher Assistance on the Outcomes of Pediatric Out-of-Hospital Cardiac Arrest.  Crit Care Med 2012 ;40(5):1410-6
+Akahane M, Tanabe T, Koike S, Ogawa T, Horiguchi H, Yasunaga H, Imamura T. Elderly out-of-hospital cardiac arrest has worse outcomes with a family bystander than a non-family bystander. Int J Emerg Med 2012;5(1):41.
+Chikuda H, Yasunaga H, Horiguchi H, Takeshita K, Kawaguchi H, Matsuda S, Nakamura K.  Mortality and morbidity in dialysis-dependent patients undergoing spinal surgery: analysis of a national administrative database in Japan.  J Bone Joint Surg Am 2012;94(5):433-8.
+Horiguchi H, Yasunaga H, Hashimoto H, Ohe K. A User-friendly Tool to Transform Large Scale Administrative Data into Wide Table Format using a MapReduce Program with a Pig Latin based Script. BMC Medical Informatics and Decision Making 2012;12:151.
+Kodama T, Koike S, Matsumoto S, Ide H, Yasunaga H, Imamura T.  The working status of Japanese female physicians by area of practice: cohort analysis of taking leave, returning to work, and changing specialties from 1984-2004.  Health Policy 2012;105(2-3):214-220
+Koike S, Ide H, Kodama T, Matsumoto S, Yasunaga H, Imamura T. Physician–Scientists in Japan: Attrition, Retention, and Implications for the Future. Academic Medicine 2012;87(5):662-7
+Masuda K, Chikuda H, Yasunaga H, Hara N, Horiguchi H, Matsuda S, Takeshita K, Kawaguchi H, Nakamura K. Factors affecting the occurrence of pulmonary embolism following spinal surgery: data from the national administrative database in Japan. Spine Journal 2012;12(11):1029-34
+Nakamura M, Yasunaga H, Miyata H, Shimada T, Horiguchi H, Matsuda S.  Mortality of Neuroleptic Malignant Syndrome Induced by Typical and Atypical Antipsychotic Drugs: A Propensity-matched Analysis from the Japanese Diagnosis Procedure Combination Database.  The Journal of Clinical Psychiatry 2012;73(4):427–430
+Nakamura M, Yasunaga H, Toda AA, Sugihara T, Imamura T. The Impact of Media Reports on the 2008 Outbreak of Hydrogen Sulfide Suicides in Japan. International Journal of Psychiatry in Medicine 2012; 44(2) 133-140.
+Sato M, Tateishi R, Yasunaga H, Horiguchi H, Yoshida H, Matsuda S, Koike K.  Mortality and morbidity of hepatectomy, radiofrequency ablation or embolization for hepatocellular carcinoma - a national survey of 54,145 patients.  J Gastroenterol 2012;47(10):1125-33 
+Shoda N, Yasunaga H, Horiguchi H, Kadono Y, Matsuda S, Tanaka S. Risk factors affecting in-hospital mortality after hip fracture: retrospective analysis using the Japanese Diagnosis Procedure Combination database. BMJ Open 2012;2(3). pii: e000416
+Sugihara T, Yasunaga H, Horiguchi H, Nakamura M, Nomiya A, Nishimatsu H, Matsuda S, Homma Y.  Admissions related to interstitial cystitis in Japan: An estimation based on the Japanese Diagnosis Procedure Combination database.  Int J Urol 2012;19:86-9.
+Sugihara T, Yasunaga H, Horiguchi H, Nishimatsu H, Fukuhara H, Enomoto Y, Kume H, Ohe K, Matsuda S, Homma Y.  Management Trends, Angioembolization Performance, and Multiorgan Injury Indicators of Renal Trauma from Japanese Administrative Claims Database.  Int J Urol 2012;19(6):559-63
+Sugihara T, Yasunaga H, Horiguchi H, Nakamura M, Nishimatsu H, Kume H, Ohe K, Matsuda S, Homma Y.  In-hospital outcomes and cost assessment between bipolar versus monopolar transurethral resection of the prostate.  Journal of Endourology 2012;26:1053-8. 
+Sugihara T, Yasunaga H, Horiguchi H, Fujimura T, Ohe K, Matsuda S, Fushimi K, Homma Y.  Impact of surgical intervention timing on Fournier’s gangrene case fatality: an analysis of 379 cases.  BJU Int 2012;110(11):E1096-100
+Sugihara T, Yasunaga H, Horiguchi H, Nishimatsu H, Hirano Y, Matsuda S, Homma Y.  Renal haemorrhage risk after extracorporeal shockwave lithotripsy: results from the Japanese Diagnosis Procedure Combination Database. BJU Int 2012;110(8 Pt B):E332-8.
+Sugihara T, Yasunaga H, Horiguchi H, Fujimura T, Nishimatsu H, Tsuru N, Kazuo S, Ohe K, Fushimi K, Homma Y. Regional, institutional and individual factors affecting selection of minimally invasive nephroureterectomy in Japan: A national database analysis. Int J Urol 2012 DOI: 10.1111/iju.12031
+Sugihara T, Yasunaga H, Horiguchi H, Tsuru N, Fujimura T, Nishimatsu H, Kume H, Ohe K, Matsuda S, Fushimi K, Homma Y. Wide Range and Variations in Minimally Invasive Surgery For Renal Malignancy in Japan: A Population Based Analysis. International Journal of Clinical Oncology 2012 10.1007/s10147-012-0500-y.
+Takeuchi M, Yasunaga H, Horiguchi H, Matsuda S.  Clinical Features of Infants Hospitalized for 2009 Pandemic Influenza A (H1N1) in Japan: Analysis Using Hospital Discharge Database. Pediatr Infect Dis J 2012;31(4):368-72
+Takeuchi M, Yasunaga H, Horiguchi H, Matsuda S.  The Incidence of pertussis hospitalizations among Japanese infants: excess hospitalizations and complications? Epidemiol Infect. 2012;140(8):1497-1502.
+Takeuchi M, Osamura T, Yasunaga H, Horiguchi H, Hashimoto H, Matsuda S. Intussusception among Japanese children: an epidemiologic study using an administrative database.  BMC Pediatrics 2012, 12:36
+Tanabe S, Yasunaga H, Ogawa T, Koike S, Akahane M, Horiguchi H, Hatanaka T, Yokota H, Imamura T. Comparison of Outcomes after Use of Biphasic or Monophasic Defibrillators Among Out-of-Hospital Cardiac Arrest Patients: A Nationwide Population-Based Observational Study. Circulation: Cardiovascular Quality and Outcomes 2012;5(5):689-96.
+Tanabe S, Yasunaga H, Koike S, Akahane M, Ogawa T, Horiguchi H, Hatanaka T, Yokota H, Imamura H. Monophasic versus biphasic defibrillation for paediatric out-of-hospital cardiac arrest patients: a nationwide population-based study in Japan. Critical Care 2012;16(6):R219.
+Uchida K, Yasunaga H. Impact of Remifentanil Use on Early Postoperative Outcomes Following Brain Tumor Resection or Rectal Cancer Surgery. Journal of Anesthesia 2012;26(5):711-20 

[2011]
+Yasunaga H, Horiguchi H, Kuwabara K, Hashimoto H, Matsuda S.  Delay in Tetracycline Treatment Increases the Risk of Complications in Tsutsugamushi Disease.  Intern Med 2011;50(1):37-42.
+Yasunaga H, Horiguchi H, Kuwabara K, Hashimoto H, Matsuda S.  Venomous Snake Bites in Japan.  Am J Trop Med Hyg 2011;84(1):135-136.
+Yasunaga H, Miyata H, Horiguchi H, Kuwabara K, Hashimoto H, Matsuda S.  Effect of the Japanese herbal Kampo medicine Dai-kenchu-to on postoperative adhesive small bowel obstruction requiring long-tube decompression: a propensity score analysis.  Evidence-Based Complementary and Alternative Medicine 2011, Article ID 264289, 7 pages
+Yasunaga H, Miyata H, Horiguchi H, Tanabe S, Akahane M, Ogawa T, Koike S, Imamura T.  Population Density, Call-response Interval, and Survival of Out-of-hospital Cardiac Arrest.  International Journal of Health Geographics 2011; 10:26.
+Yasunaga H, Sugihara T, Imamura T.  Difference in Willingness-to-pay for Prostate Cancer Screening between Ill-informed and Well-informed Men: A Contingent Valuation Survey.  Urology 2011;77(6):1325-9.
+Akahane M, Ogawa T, Koike S, Tanabe S, Horiguchi H, Mizoguchi T, Yasunaga H, Imamura T.  The effects of sex on out-of-hospital cardiac arrest outcomes.  The American Journal of Medicine 2011;124(4):325-33
+Hashimoto H, Ikegami N, Shibuya K, Izumida N, Noguchi H, Yasunaga H, Miyata H, Acuin JM, Reich MR.  Cost containment and quality of care in Japan: is there a trade-off?  Lancet 2011;378(9797):1174-1182.
+Horiguchi H, Yasunaga H, Hashimoto H, Matsuda S.  Incidence of severe adverse events requiring hospital care after trastuzumab infusion for metastatic breast cancer: a nationwide survey using an administrative claim database.  Breast J 2011;17(6):683-5.
+Koike K, Tanabe T, Ogawa T, Akahane M, Yasunaga H, Horiguchi H, Matsumoto S, Imamura T.  Effect of time and day of admission on 1-month survival and neurologically favourable 1-month outcome in out-of-hospital cardiopulmonary arrest patients.  Resuscitation 2011;82(7):863-8.
+Koike S, Tanabe T, Ogawa T, Akahane M, Yasunaga H, Horiguchi H, Matsumoto S, Imamura T.  Immediate defibrillation or defibrillation after cardiopulmonary resuscitation.  Prehospital Emergency Care 2011; 15(3):393-400.
+Koike S, Ogawa T, Tanabe T, Matsumoto S, Akahane M, Yasunaga H, Horiguchi H, Imamura T.  Collapse-to-emergency medical service cardiopulmonary resuscitation interval and outcomes of out-of-hospital cardiopulmonary arrest: a nationwide observational study.  Critical Care 2011 2011;15:R120.
+Kuwabara K, Matsuda S, Fushimi K, Ishikawa KB, Horiguchi H, Fujimori K, Yasunaga H, Miyata H.  Quantitative Assessment of the Advantages of Laparoscopic Gastrectomy and the Impact of Volume-Related Hospital Characteristics on Resource Use and Outcomes of Gastrectomy Patients in Japan.  Ann Surg 2011;253(1):64-70.
+Nagase Y, Yasunaga H, Horiguchi H, Hashimoto H, Shoda N, Kadono Y, Matsuda S, Nakamura K, Tanaka S.  Risk factors for pulmonary embolism and the effects of fondaparinux after total hip and knee arthroplasty: a retrospective observational study with use of a national database in Japan.  J Bone Joint Surg Am 2011; 93:e146 (1-7).
+Otake H, Yasunaga H, Horiguchi H, Matsutani N, Matsuda S, Ohe K.  Impact of hospital volume on chest tube duration, length of stay and mortality following lobectomy.  Ann Thorac Surg 2011;92:1069-75.
+Sako A, Yasunaga H, Horiguchi H, Hashimoto H, Masaki N, Matsuda S.  Acute Hepatitis B in Japan: Incidence, Clinical Practices and Health Policy.  Hepatol Res 2011;41(1):39-45.
+Sugihara H, Yasunaga H, Horiguchi H, Nishimatsu H, Kume H, Matsuda S, Homma Y.  Impact of Hospital Volume and Laser Usage on Postoperative Complications and In-hospital Mortality After Transurethral Surgery of Benign Prostate Hyperplasia: Japanese Diagnosis Procedure Combination Database.  J Urol 2011;185:2248-2253.
+Sugihara T, Yasunaga H, Horiguchi H, Nishimatsu H, Matsuda S, Homma Y.  Incidence rate and clinical features of priapism in Japan; 46 cases from Japanese Diagnosis Procedure Combination database 2006-2008.  International Journal of Impotence Research 2011;23(2):76-80.
+Sumitani M, Uchida K, Yasunaga H, Horiguchi H, Kusakabe Y, Matsuda S, Yamada Y.  Prevalence of Malignant Hyperthermia and Relationship with Anesthetics in Japan: Data from the Diagnosis Procedure Combination Database.  Anesthesiology 2011;114(1):84-90.
+Uchida K, Yasunaga H, Miyata H, Sumitani M, Horiguchi H, Kuwajima K, Matsuda S, Yamada Y.  Impact of remifentanil introduction on practice patterns in general anesthesia.  J Anesth 2011;25(6):864-71.

[2010]
+Yasunaga H, Horiguchi H, Kuwabara K, Hashimoto H, Matsuda S.  Clinical features of Bowel Anisakiasis in Japan.  Am J Trop Med Hyg 2010; 83: 104-105.
+Yasunaga H, Horiguchi H, Tanabe S, Akahane M, Ogawa T, Koike S, Imamura T.  Collaborative effects of bystander-initiated cardiopulmonary resuscitation and prehospital advanced cardiac life support by physicians on survival of out-of-hospital cardiac arrest: a nationwide population-based observational study.  Critical Care 2010;14(6):R199.
+Yasunaga H, Shi Y, Takeuchi M, Horiguchi H, Hashimoto H, Matsuda S, Ohe K.  Measles-related Hospitalizations and Complications in Japan, 2007-2008.  Internal Medicine 2010; 49: 1965-1970.
+Yasunaga H, Yanaihara H, Fuji K, Horiguchi H, Hashimoto H, Matsuda S.  Impact of hospital volume on postoperative complications and in-hospital mortality following renal surgery: data from the Japanese diagnosis procedure combination database.  Urology 2010; 76: 548–552
+Horiguchi H, Yasunaga H, Hashimoto H, Matsuda S.  Impact of drug-eluting stents on treatment option mix for coronary artery disease in Japan.  Circ J 2010;74(8):1635-1643.
+Ide H, Koike S, Yasunaga H, Kodama T, Ohe K, Imamura T.  Long-term Career Transition in the Surgical Workforce of Japan: A Retrospective Cohort Study Using the Nationwide Survey of Physicians Data from 1972 to 2006.  World J Surg 2010;34(8):1748-1755.
+Kadono Y, Yasunaga H, Horiguchi H, Hashimoto H, Matsuda S, Tanaka S, Nakamura K.  Statistics in orthopaedic surgery 2006-2007: Data from the Japanese Diagnosis Procedure Combination (DPC) database.  J Orthop Sci 2010; 15: 162-70
+Koike S, Ide H, Yasunaga H, Kodama T, Matsumoto S, Imamura T.  Postgraduate training and career choices: an analysis of the National Physicians Survey in Japan.  Medical Education 2010;44: 289-297.
+Koike S, Kodama T, Matsumoto S, Ide H, Yasunaga H, Imamura T.  Residency Hospital Type and Career Paths in Japan: An Analysis of Physician Registration Cohorts. Medical Teacher 2010;32(6):e239-47.
+Koike S, Kodama T, Matsumoto S, Ide H, Yasunaga H, Imamura T.  Retention rate of physicians in public health administration agencies and their career paths in Japan.  BMC Health Services Research 2010, 10:101.
+Koike S, Matsumoto S, Kodama T, Ide H, Yasunaga H, Imamura T.  Specialty choice and physicians’ career paths in Japan: An analysis of National Physician Survey data from 1996 to 2006.  Health Policy 2010;98:236-244.
+Kuwabara K, Matsuda S, Imanaka Y, Fushimi K, Hashimoto H, Ishikawa KB, Horiguchi H, Hayashida K, Fujimori K, Ikeda S, Yasunaga H.  Injury Severity Score, resource use, and outcome for trauma patients within a Japanese administrative database.  The Journal of Trauma: Injury, Infection and Critical Care 2010;68(2):463-70.
+Matsui H, Hashimoto H, Horiguchi H, Yasunaga H, Matsuda S.  An exploration of the association between very early rehabilitation and outcome for the patients with acute ischaemic stroke in Japan: a nationwide retrospective cohort survey.  BMC Health Services Research 2010;10:213.
ここは旧HPのアドレスです。
新アドレスは[こちら|http://www.heer.m.u-tokyo.ac.jp/]です。